Eastern European Bladder Cancer Study
Study Name: Eastern European Bladder Cancer Study
Principal Investigators: Tony Fletcher
Additional researchers:
Institution: PEHRU Public and Environmental Health Research Unit, London School of Hygiene & Tropical Medicine
Institution address:
PEHRU Public and Environmental Health Research Unit,\
London School of Hygiene & Tropical Medicine
Keppel Street
London WC1E 7HT, UK
Key References:
Study Design: Hospital-based case control
Matching factors: Age, gender
Country: Hungary, Romania, Slovakia
ICD-0-3 morphology codes:
Follow up of cases? No
Expected time of follow-up? NA
Urinary Bladder ICD-0-3 morphology codes: Transitional cell carcinoma (81203); Papillary carcinoma (81303); Squamous cell carcinoma (80703); Adenocarcinoma (81403); Leiomyosarcoma (88903)
Cases | Controls | |
---|---|---|
Years of enrollment | 2002-2004 | 2002-2004 |
Source population | Hungary, Romania and Slovakia | Hungary, Romania and Slovakia |
Response rate (enrolled/eligible) | 85.3% | |
Total number enrolled | 214 | 540 |
Subjects with DNA | 214 | 540 |
Ethnic origin | Caucasian | Caucasian |
Age: mean (range) | 30-79 | 30-79 |
Gender: % males |
Questionnaire data | Cases | Controls |
---|---|---|
Demographics (age, sex, ethnicity, region, education etc..) | x | x |
Active smoking | x | x |
Passive smoking | x | x |
Occupational exposures | x | x |
Residential history | x | x |
Water chlorination byproducts | - | - |
Arsenic exposure | x | x |
Other environmental exposures | - | - |
Hair dye use | - | - |
Drug use | x | x |
Medical History | x | x |
Family History | x | x |
Quality of life | - | - |
Diet/nutrition | x | x |
Caffeine intake | x | x |
Fluid intake | x | x |
Urine pH measurements | - | - |
Other information, please specify | x | x |
Biological Samples | Cases | Controls |
---|---|---|
Blood DNA | x | x |
Buccal DNA | x | x |
Serum/plasma | - | - |
Cryopreserved whole blood / lymphocytes | - | - |
Red blood cells | - | - |
Urine samples | - | - |
Toenail clippings | - | - |
Others, please specify | - | - |
Paraffin tissue blocks | - | |
Frozen tissue | - |
For Cases Only | |
Information at time of diagnosis | Cases |
---|---|
Histological confirmation | x |
Number of tumors | - |
Tumor site | - |
Tumor size | - |
Tumor grade | x |
Growth pattern | - |
Treatment of primary tumor | - |
Stage | - |
Other information, please specify | - |
Follow-up information | Cases |
---|---|
Treatment information | - |
Tumor recurrence | - |
Tumor progression | - |
Survival | - |
Histological confirmation | - |
Number of tumors | - |
Tumor site | - |
Tumor size | - |
Tumor grade | - |
Growth pattern | - |
Stage | - |
Active smoking | - |
Occupational exposures | - |
Drug use | - |
Medical History | - |
Quality of life | - |
Caffeine intake | - |
Fluid intake | - |
Other information , please specify | - |