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Torino Bladder Cancer
Study Name:Torino Bladder Cancer
Principal Investigators:
Giuseppe Matullo
Paolo Vineis
Additional researchers: Carlotta Sacerdote
Institution: Dipartimento di Scienze Biomediche e Oncologia Umana
Institution address: Via Santena 7 10126 Torino Italy
Key References:
Study Design: Hospital-based case control
Matching factors:
Country: Italy
ICD-0-3 morphology codes: 81203, 81303, 80703, 81403, 81402
Follow up of cases? Yes
Expected time of follow-up? 15/07/2007
Urinary Bladder ICD-0-3 morphology codes: Transitional cell carcinoma (81203); Papillary carcinoma (81303); Squamous cell carcinoma (80703); Adenocarcinoma (81403); Leiomyosarcoma (88903)
| Cases | Controls | |
|---|---|---|
| Years of enrollment | 1994-2007 | 1994-2007 |
| Source population | Torino metropolitan area | Torino metropolitan area |
| Response rate (enrolled/eligible) | ||
| Total number enrolled | 439 | 512 |
| Subjects with DNA | 422 | 414 |
| Ethnic origin | 100% Italian Caucasian | |
| Age: mean (range) | 57.3 (42-74) | 57.3 (40-74) |
| Gender: % males | 100% | 100% |
| Questionnaire data | Cases | Controls |
|---|---|---|
| Demographics (age, sex, ethnicity, region, education etc..) | x | x |
| Active smoking | x | x |
| Passive smoking | x | x |
| Occupational exposures | x | x |
| Residential history | - | - |
| Water chlorination byproducts | - | - |
| Arsenic exposure | - | - |
| Other environmental exposures | - | - |
| Hair dye use | - | - |
| Drug use | x | x |
| Medical History | - | - |
| Family History | x | x |
| Quality of life | - | - |
| Diet/nutrition | x | x |
| Caffeine intake | x | x |
| Fluid intake | x | x |
| Urine pH measurements | - | - |
| Other information, please specify | - | - |
| Biological Samples | Cases | Controls |
|---|---|---|
| Blood DNA | x | x |
| Buccal DNA | - | - |
| Serum/plasma | x | x |
| Cryopreserved whole blood / lymphocytes | x | - |
| Red blood cells | - | - |
| Urine samples | x | x |
| Toenail clippings | - | - |
| Others, please specify | - | - |
| Paraffin tissue blocks | - | |
| Frozen tissue | - |
| For Cases Only | |
| Information at time of diagnosis | Cases |
|---|---|
| Histological confirmation | x |
| Number of tumors | - |
| Tumor site | x |
| Tumor size | x |
| Tumor grade | x |
| Growth pattern | - |
| Treatment of primary tumor | x |
| Stage | - |
| Other information, please specify Morphology | x |
| Follow-up information | Cases |
|---|---|
| Treatment information | - |
| Tumor recurrence | - |
| Tumor progression | - |
| Survival | x |
| Histological confirmation | - |
| Number of tumors | - |
| Tumor site | - |
| Tumor size | - |
| Tumor grade | - |
| Growth pattern | - |
| Stage | - |
| Active smoking | - |
| Occupational exposures | - |
| Drug use | - |
| Medical History | - |
| Quality of life | - |
| Caffeine intake | - |
| Fluid intake | - |
| Other information , please specify: Cause of death | x |